Diabetes insipidus in sellar-suprasellar tuberculoma

J Clin Neurosci. 2003 Jul;10(4):497-9. doi: 10.1016/s0967-5868(02)00285-0.


Tuberculoma involving the sellar and suprasellar region is extremely rare. Sellar region tuberculoma usually presents with endocrinopathy of hypofunction, rarely hyperfunction or normal function of the anterior pituitary. However, sellar-suprasellar tuberculoma presenting with diabetes insipidus (DI) is very rare. We report the case of a 32 year old housewife presenting with DI and secondary amenorrhea, who had a sellar-suprasellar mass on MRI. She underwent a transnasal transsphenoidal surgical removal of the pituitary mass, which was tubercular in nature on histology. She received antitubercular treatment and hormonal replacement therapy. She was well at last follow-up, 3 years after surgery.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diabetes Insipidus / etiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Pituitary Diseases / complications*
  • Pituitary Diseases / pathology
  • Pituitary Diseases / surgery
  • Tuberculoma / complications*
  • Tuberculoma / pathology
  • Tuberculoma / surgery*