1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin

Pol J Pharmacol. Jan-Feb 2003;55(1):109-12.

Abstract

It has been found that 1-methylnicotinamide (MNA+), a metabolite of nicotinamide, possesses significant anti-inflammatory properties. MNA+ is chemically stable, non-toxic and well tolerated. MNA+ can be used to treat wide variety of diseases and disorders and the use of this compound provides certain advantages over the use of nicotinamide.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / metabolism*
  • Dermatitis / metabolism
  • Dermatitis / prevention & control
  • Double-Blind Method
  • Gels
  • Humans
  • Niacinamide / administration & dosage*
  • Niacinamide / analogs & derivatives*
  • Niacinamide / chemistry
  • Niacinamide / metabolism*
  • Pilot Projects

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Gels
  • Niacinamide
  • N(1)-methylnicotinamide