Abstract
When the polysaccharide from Grifola frondosa (PGF) was taken orally by S180 bearing mice at the dosage of 50-150 mg/kg.d for 9 d, the inhibitory rate to S180 was 27.97%-38.46%. The PGF can also enhance thymus index, the ability of splenic lymphocyte proliferation and formation of antibody in splenic cells, and promote the production of IgM hemolysin significantly in S-180 bearing mice.
MeSH terms
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Adjuvants, Immunologic / pharmacology*
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Agaricales / chemistry*
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Animals
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Antibody Formation / drug effects
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Antineoplastic Agents / pharmacology*
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Drugs, Chinese Herbal / pharmacology*
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Female
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Hemolysin Proteins / blood
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Lymphocyte Activation / drug effects
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Mice
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Polysaccharides / isolation & purification
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Polysaccharides / pharmacology*
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Sarcoma 180 / drug therapy
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Sarcoma 180 / immunology*
Substances
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Adjuvants, Immunologic
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Antineoplastic Agents
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Drugs, Chinese Herbal
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Hemolysin Proteins
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Polysaccharides