[Anti-tumor effect of polysaccharide from Grifola frondosa and its influence on immunological function]

Zhong Yao Cai. 2003 Jan;26(1):31-2.
[Article in Chinese]

Abstract

When the polysaccharide from Grifola frondosa (PGF) was taken orally by S180 bearing mice at the dosage of 50-150 mg/kg.d for 9 d, the inhibitory rate to S180 was 27.97%-38.46%. The PGF can also enhance thymus index, the ability of splenic lymphocyte proliferation and formation of antibody in splenic cells, and promote the production of IgM hemolysin significantly in S-180 bearing mice.

Publication types

  • English Abstract

MeSH terms

  • Adjuvants, Immunologic / pharmacology*
  • Agaricales / chemistry*
  • Animals
  • Antibody Formation / drug effects
  • Antineoplastic Agents / pharmacology*
  • Drugs, Chinese Herbal / pharmacology*
  • Female
  • Hemolysin Proteins / blood
  • Lymphocyte Activation / drug effects
  • Mice
  • Polysaccharides / isolation & purification
  • Polysaccharides / pharmacology*
  • Sarcoma 180 / drug therapy
  • Sarcoma 180 / immunology*

Substances

  • Adjuvants, Immunologic
  • Antineoplastic Agents
  • Drugs, Chinese Herbal
  • Hemolysin Proteins
  • Polysaccharides