Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women

Am J Obstet Gynecol. 2003 Jul;189(1):239-44. doi: 10.1067/mob.2003.441.


Objective: This study was undertaken to investigate the relationship between pregnancy outcome and prepregnancy overweight or obesity in women with a normal glucose tolerance test.

Study design: A historical cohort study of 2459 pregnant women systematically examined for gestational diabetes was performed. Information of oral glucose tolerance test results and clinical outcome were collected from medical records.

Results: The risk of hypertensive complications, cesarean section, induction of labor and macrosomia was significantly increased in both overweight women (body mass index [BMI] 25.0-29.9 kg/m(2)) and obese women (BMI >or= 30.0 kg/m(2)) compared with women who were of normal weight (BMI 18.5-24.9 kg/m(2)). The frequencies of shoulder dystocia, preterm delivery, and infant morbidity other than macrosomia were not significantly associated with maternal BMI.

Conclusion: Prepregnancy overweight and obesity is associated with adverse pregnancy outcome in glucose-tolerant women.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index*
  • Cesarean Section / statistics & numerical data
  • Cohort Studies
  • Denmark
  • Diabetes, Gestational / diagnosis
  • Dystocia / epidemiology
  • Female
  • Fetal Macrosomia / epidemiology
  • Glucose Tolerance Test*
  • Humans
  • Hypertension / complications
  • Labor, Induced / statistics & numerical data
  • Obesity / complications*
  • Obstetric Labor, Premature / epidemiology
  • Pregnancy
  • Pregnancy Complications*
  • Pregnancy Outcome*
  • Weight Gain