Maximizing the safety of nonsteroidal anti-inflammatory drug use for postoperative dental pain: an evidence-based approach

K S Ong; R A Seymour

Maximizing the safety of nonsteroidal anti-inflammatory drug use for postoperative dental pain: an evidence-based approach

Anesth Prog. 2003;50(2):62-74.

Authors

K S Ong¹, R A Seymour

Affiliation

¹ Department of Oral and Maxillofacial Surgery, National University of Singapore. cliffong@pacific.net.sg

PMID: 12866802
PMCID: PMC2007429

Abstract

This article reviews the use of nonsteroidal anti-inflammatory drugs (NSAIDs) for postoperative dental pain. An evidence-based approach is used to evaluate the clinical studies to date on the safe use of these drugs in dental patients. No drugs are without adverse effects or are perfectly safe, but their safe use in clinical practice would entail maximizing the therapeutic efficacy and minimizing the adverse effects. Therapeutic recommendations are made after reviewing the evidence for the safe use of NSAIDs in postoperative dental pain.

Publication types

Review

MeSH terms

Acute Kidney Injury / chemically induced
Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
Anti-Inflammatory Agents, Non-Steroidal / adverse effects
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Bronchoconstriction
Cyclooxygenase Inhibitors / adverse effects
Cyclooxygenase Inhibitors / therapeutic use
Drug Interactions
Evidence-Based Medicine
Humans
Models, Biological
Molar, Third / surgery*
Oral Hemorrhage / chemically induced
Postoperative Hemorrhage / chemically induced
Postoperative Pain / drug therapy*
Postoperative Pain / etiology
Tooth Extraction / adverse effects*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase Inhibitors