Monocyte heterogeneity and innate immunity

Immunity. 2003 Jul;19(1):2-4. doi: 10.1016/s1074-7613(03)00178-x.


Peripheral monocyte heterogeneity is widely acknowledged in humans but until now comparable heterogeneity has not been characterized in mice. In this issue, Geissmann et al. use chemokine receptors to define two monocyte subsets and Serbina et al. highlight the importance of selective monocyte recruitment in the innate immune response to Listeria.

Publication types

  • Comment

MeSH terms

  • Cell Movement
  • Dendritic Cells / physiology
  • Humans
  • Immunity, Innate*
  • Monocytes / physiology*
  • Receptors, CCR2
  • Receptors, Chemokine / physiology


  • CCR2 protein, human
  • Receptors, CCR2
  • Receptors, Chemokine