Striking improvement of muscle strength under creatine therapy in a patient with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

G C Korenke; R J A Wanders; F Hanefeld

doi:10.1023/a:1024031714659

Striking improvement of muscle strength under creatine therapy in a patient with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

J Inherit Metab Dis. 2003;26(1):67-8. doi: 10.1023/a:1024031714659.

Authors

G C Korenke¹, R J A Wanders, F Hanefeld

Affiliation

¹ Department of Paediatrics and Neuropaediatrics, University of Göttingen, Göttingen, Germany.

PMID: 12872842
DOI: 10.1023/a:1024031714659

Abstract

Creatine monohydrate given orally led to a long-lasting improvement of muscular weakness and ataxia in a girl with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.

Publication types

Case Reports

MeSH terms

3-Hydroxyacyl CoA Dehydrogenases / deficiency*
Child
Creatine / therapeutic use*
Female
Humans
Lipid Metabolism, Inborn Errors / drug therapy*
Lipid Metabolism, Inborn Errors / physiopathology*
Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase
Muscle Weakness / drug therapy*
Muscle Weakness / etiology*
Muscle, Skeletal / physiopathology*
Recurrence
Rhabdomyolysis / etiology

Substances

3-Hydroxyacyl CoA Dehydrogenases
Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase
Creatine