Visual field defects after uneventful vitrectomy for epiretinal membrane with indocyanine green-assisted internal limiting membrane peeling

Am J Ophthalmol. 2003 Aug;136(2):252-7. doi: 10.1016/s0002-9394(03)00157-0.


Purpose: To report visual field defects after vitrectomy for epiretinal membrane with indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling.

Design: Interventional consecutive case series.

Methods: A retrospective review of 16 eyes of 16 patients who underwent vitrectomy for idiopathic epiretinal membrane. Indocyanine green-assisted ILM peeling was performed in 7 of 16 eyes. The main outcome measure was postoperative visual field.

Results: Four of seven eyes (57%) with ICG-assisted ILM peeling had visual field defects postoperatively. The field defects identified were nasal in three eyes; in the fourth eye, the visual field was constricted to approximately 30 degrees. None of the nine eyes without ICG-assisted ILM peeling had a visual field defect.

Conclusions: Peripheral visual field defects may occur after vitrectomy with ICG-assisted ILM peeling. Although the cause of the defects is unclear, the potential role of ICG toxicity requires further investigation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Basement Membrane / pathology
  • Basement Membrane / surgery*
  • Coloring Agents
  • Epiretinal Membrane / diagnosis
  • Epiretinal Membrane / surgery*
  • Female
  • Humans
  • Indocyanine Green*
  • Male
  • Middle Aged
  • Postoperative Complications*
  • Retrospective Studies
  • Vision Disorders / etiology*
  • Visual Acuity
  • Visual Field Tests
  • Visual Fields*
  • Vitrectomy*


  • Coloring Agents
  • Indocyanine Green