VIM- And IMP-type Metallo-Beta-Lactamase-Producing Pseudomonas Spp. And Acinetobacter Spp. In Korean Hospitals

Emerg Infect Dis. 2003 Jul;9(7):868-71. doi: 10.3201/eid0907.020753.

Abstract

We determined the occurrence of acquired metallo-b-lactamase (MBL)-producing bacteria in Korean hospitals. Among the isolates nonsusceptible to imipenem that were collected from 28 hospitals from 2000 to 2001, 44 (11.4%) of 387 Pseudomonas spp. and 38 (14.2%) of 267 Acinetobacter spp. produced MBL and had alleles of blaVIM-2 or blaIMP-1. MBL-producing isolates were detected in 60.7% of the hospitals.

MeSH terms

  • Acinetobacter / classification
  • Acinetobacter / drug effects
  • Acinetobacter / enzymology*
  • Acinetobacter Infections / microbiology*
  • Alleles
  • Anti-Bacterial Agents / pharmacology
  • Drug Resistance, Multiple, Bacterial / genetics
  • Hospitals
  • Humans
  • Korea
  • Pseudomonas / classification
  • Pseudomonas / drug effects
  • Pseudomonas / enzymology*
  • Pseudomonas Infections / microbiology*
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • VIM-1 metallo-beta-lactamase
  • beta-lactamase IMP-1
  • beta-Lactamases