Lipids in endocytic membrane transport and sorting

Curr Opin Cell Biol. 2003 Aug;15(4):382-8. doi: 10.1016/s0955-0674(03)00078-4.

Abstract

Protein complexes associated to specific membrane lipids and protein-lipid domains contribute to regulate protein sorting and membrane dynamics in the endocytic pathway. It is also becoming apparent that different lipid territories are distributed along the pathway, and that some lipids segregate into specialised microdomains.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Compartmentation / physiology
  • Endocytosis / physiology*
  • Endosomes / metabolism
  • Humans
  • Intracellular Membranes / metabolism*
  • Membrane Lipids / metabolism*
  • Phosphatidylinositols / metabolism
  • Protein Transport / physiology*
  • Transport Vesicles / metabolism*

Substances

  • Membrane Lipids
  • Phosphatidylinositols