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Case Reports
, 201 (10), 1580-3

Phenobarbital-responsive Episodic Dyscontrol (Rage) in Dogs

  • PMID: 1289339
Case Reports

Phenobarbital-responsive Episodic Dyscontrol (Rage) in Dogs

N H Dodman et al. J Am Vet Med Assoc.


Episodic dyscontrol (rage) was diagnosed from the clinical history, electroencephalographic findings, and response to oral treatment with phenobarbital in 3 dogs. Clinical features included a mood change heralding aggressive incidents, explosive aggression directed at people or objects, and a postaggressive phase characterized by lethargy and lack of responsiveness. Abnormal electroencephalographic findings included spike activity in the temporal recordings. All 3 dogs responded well to anticonvulsant medication with phenobarbital.

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