Phenobarbital-responsive episodic dyscontrol (rage) in dogs

J Am Vet Med Assoc. 1992 Nov 15;201(10):1580-3.

Abstract

Episodic dyscontrol (rage) was diagnosed from the clinical history, electroencephalographic findings, and response to oral treatment with phenobarbital in 3 dogs. Clinical features included a mood change heralding aggressive incidents, explosive aggression directed at people or objects, and a postaggressive phase characterized by lethargy and lack of responsiveness. Abnormal electroencephalographic findings included spike activity in the temporal recordings. All 3 dogs responded well to anticonvulsant medication with phenobarbital.

Publication types

  • Case Reports

MeSH terms

  • Aggression / drug effects*
  • Animals
  • Behavior, Animal / drug effects*
  • Dog Diseases / drug therapy*
  • Dogs
  • Electroencephalography / veterinary
  • Epilepsy, Temporal Lobe / drug therapy
  • Epilepsy, Temporal Lobe / veterinary*
  • Follow-Up Studies
  • Male
  • Phenobarbital / pharmacology
  • Phenobarbital / therapeutic use*
  • Syndrome

Substances

  • Phenobarbital