Abstract
We report that the anti-retroviral and anti-hepadnavirus molecules, adefovir, tenofovir and 9-(2-phosphonomethoxyethyl)-2,6-diaminopurine (PMEDAP), efficiently eradicate the episomal form of Banana streak virus (BSV) from banana plants. Up to 90% of plants regenerated from BSV-infected highly proliferating meristems were virus free following a 6-month treatment period with 10 microg/ml (a non-phytotoxic concentration) of either compounds.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenine / analogs & derivatives*
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Adenine / pharmacology
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Adenine / toxicity
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Antiviral Agents / pharmacology*
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Antiviral Agents / toxicity
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Badnavirus / drug effects*
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Badnavirus / pathogenicity
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Badnavirus / physiology
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Musa / drug effects*
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Musa / virology*
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Organophosphonates*
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Organophosphorus Compounds / pharmacology
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Organophosphorus Compounds / toxicity
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Plant Diseases / virology*
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Reverse Transcriptase Inhibitors / pharmacology
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Reverse Transcriptase Inhibitors / toxicity
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Tenofovir
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Virus Replication / drug effects
Substances
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Antiviral Agents
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Organophosphonates
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Organophosphorus Compounds
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Reverse Transcriptase Inhibitors
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9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine
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adefovir
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Tenofovir
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Adenine