Comparison of I-123 IMP and Ga-67 citrate scintigraphy of malignant melanoma

Clin Nucl Med. 2003 Aug;28(8):704-8. doi: 10.1097/


I-123 iodoamphetamine (IMP) and Ga-67 scintigraphy of malignant melanoma were performed to compare the accumulation of these tracers regarding tumor diameter to determine the site of I-123 IMP accumulation and to evaluate the use of I-123 IMP and Ga-67 in postoperative follow-up. The studies involved 44 patients with a definite diagnosis of malignant melanoma during a 10-year period from April 1991 through March 2001. In this study a very high detection rate of 90.9% was obtained for primary foci with I-123 IMP. With Ga-67, the primary site detection rate was 25%. The results suggest that I-123 IMP is superior to Ga-67 with respect to the detection rate of primary site.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Aged
  • Citrates* / pharmacokinetics
  • Female
  • Gallium* / pharmacokinetics
  • Humans
  • Iofetamine* / pharmacokinetics
  • Male
  • Melanoma / diagnostic imaging*
  • Melanoma / metabolism
  • Melanoma / secondary
  • Middle Aged
  • Postoperative Care
  • Predictive Value of Tests
  • Radionuclide Imaging
  • Radiopharmaceuticals / pharmacokinetics


  • Citrates
  • Radiopharmaceuticals
  • Iofetamine
  • Gallium
  • gallium citrate