The effect of physical exercise on reverse cholesterol transport

Metabolism. 2003 Aug;52(8):950-7. doi: 10.1016/s0026-0495(03)00147-1.


High-density lipoproteins (HDL) are recognized for their role in coronary artery disease (CAD) risk reduction. Plasma HDL plays a pivotal role in the reverse cholesterol transport (RCT) process. Physical exercise is well recognized as a modality that affects HDL metabolism. The purpose of this discussion is to describe the effects of physical exercise on RCT.

Publication types

  • Review

MeSH terms

  • Apolipoprotein A-I / metabolism
  • Biological Transport, Active / physiology
  • Cholesterol / metabolism*
  • Cholesterol, HDL / metabolism
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / physiopathology
  • Exercise / physiology*
  • Humans


  • Apolipoprotein A-I
  • Cholesterol, HDL
  • Cholesterol