In vitro human phase I metabolism of xenobiotics I: pesticides and related compounds used in agriculture and public health, May 2003

J Biochem Mol Toxicol. 2003;17(4):201-6. doi: 10.1002/jbt.10080.

Abstract

This is the first revision of a database covering human phase I enzymes and their isoforms that metabolize pesticides and related compounds. The original version included enzymes that metabolize chloroacetamide and triazine herbicides, and organophosphorus insecticides. This revision also includes carbamate, nicotinoid, and pyrethroid insecticides and insect repellents.

MeSH terms

  • Agriculture*
  • Animals
  • Cytochrome P-450 Enzyme System / metabolism
  • Databases, Protein*
  • Herbicides / metabolism
  • Humans
  • Insecticides / metabolism
  • Isoenzymes / metabolism
  • Pesticides / metabolism*
  • Public Health*
  • Xenobiotics / metabolism*

Substances

  • Herbicides
  • Insecticides
  • Isoenzymes
  • Pesticides
  • Xenobiotics
  • Cytochrome P-450 Enzyme System