The sensory circumventricular organs of the mammalian brain

Adv Anat Embryol Cell Biol. 2003:172:III-XII, 1-122, back cover. doi: 10.1007/978-3-642-55532-9.


The brain's three sensory circumventricular organs, the subfornical organ, organum vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and are the only regions in the brain in which neurons are exposed to the chemical environment of the systemic circulation. Therefore they are ideally placed to monitor the changes in osmotic, ionic and hormonal composition of the blood. This book describes their. General structure and relationship to the cerebral ventricles Regional subdivisions Vasculature and barrier properties Neurons, glia and ependymal cells Receptors, neurotransmitters, neuropeptides and enzymes Neuroanatomical connections Functions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Area Postrema / anatomy & histology*
  • Area Postrema / physiology*
  • Cerebral Ventricles / anatomy & histology
  • Cerebral Ventricles / physiology
  • Ependyma / anatomy & histology
  • Ependyma / physiology
  • Humans
  • Mammals
  • Subfornical Organ / anatomy & histology*
  • Subfornical Organ / physiology*