Abstract
T helper (Th)2 cell-mediated immune responses are associated with parasitic helminth infections and atopic disorders. The production of interleukin (IL)-4, IL-5, IL-9 and/or IL-13 by Th2 cells mediates a range of responses that can be protective or pathogenic. Progress has recently been made in elucidating the mechanism of Th2 immunity, which has therapeutic potential for the treatment of allergic diseases.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
Cytokines / genetics
-
Cytokines / immunology*
-
Drug Delivery Systems
-
Gene Silencing
-
Humans
-
Hypersensitivity / immunology
-
Hypersensitivity / therapy
-
Immunotherapy*
-
Receptors, Cytokine / metabolism
-
Th1 Cells / immunology
-
Th1 Cells / pathology
-
Th2 Cells / immunology*
-
Th2 Cells / pathology
Substances
-
Cytokines
-
Receptors, Cytokine