Clinical presentation of peritoneal mesothelioma

Tumori. May-Jun 2003;89(3):269-73.


Aim: To describe the clinical presentation of peritoneal mesothelioma and its impact on survival.

Methods: Data was collected from 51 patients with peritoneal mesothelioma treated at the Washington Cancer Institute. The demographic, clinical and pathologic information were analyzed.

Results: Pain was the most common symptom (recorded in 33% of patients); increased abdominal girth occurred in 31%, increased abdominal girth and pain in 5%, and a new onset hernia in 12%. In an additional 14% of patients, a variety of other clinical findings led to the diagnosis. There was a statistically significant difference in survival by gender, weight loss and volume of disease.

Conclusions: Pain was the most common initial presenting symptom, with increased abdominal girth as a second. A more favorable prognosis occurred in women with a small disease volume.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Ascites / pathology
  • Combined Modality Therapy
  • Female
  • Fever / diagnosis
  • Follow-Up Studies
  • Humans
  • Male
  • Mesothelioma / diagnosis*
  • Middle Aged
  • Neoplasm Staging
  • Pain / diagnosis
  • Peritoneal Neoplasms / diagnosis*
  • Prognosis
  • Survival Rate
  • Weight Loss