[The fMRI study of the calculation tasks in normal aged volunteers]

Beijing Da Xue Xue Bao Yi Xue Ban. 2003 Jun 18;35(3):311-3.
[Article in Chinese]


Objective: To investigate the feasibility and cortex activation of fMRI in aged volunteers during the performance of calculation tasks.

Methods: Internal mental calculation tasks including simple tasks and complicated tasks were conducted in 11 normal aged volunteers. The fMRI data was postprocessed using SPM99 to reveal the activated cortex.

Results: The simple calculation tasks were fulfilled satisfactorily in all aged subjects. Cortex in the bilateral Superior parietal lobule, inferior parietal lobule and bilateral occipital lobes showed activation. We found a selective enhancement of fMRI signal in Brodmann regions 9, 10 and 46 in the complicated tasks.

Conclusion: fMRI tasks are feasible in aged people and more cortex of the left frontal lobe shows activation in complicated calculation tasks.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Brain / physiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male