Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers

Indian J Physiol Pharmacol. 1992 Oct;36(4):273-5.


The effect of curcumin administration in reducing the serum levels of cholesterol and lipid peroxides was studied in ten healthy human volunteers, receiving 500 mg of curcumin per day for 7 days. A significant decrease in the level of serum lipid peroxides (33%), increase in HDL Cholesterol (29%), and a decrease in total serum cholesterol (11.63%) were noted. As curcumin reduced serum lipid peroxides and serum cholesterol, the study of curcumin as a chemopreventive substance against arterial diseases is suggested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Adult
  • Body Weight / drug effects
  • Cholesterol / blood*
  • Cholesterol, HDL / blood
  • Curcumin / pharmacology*
  • Female
  • Humans
  • Lipid Peroxides / blood*
  • Male
  • Middle Aged
  • Triglycerides / blood


  • Cholesterol, HDL
  • Lipid Peroxides
  • Triglycerides
  • Cholesterol
  • Curcumin