Purkinje-like cells in the cochlear nucleus of the Common Tree Shrew (Tupaia glis) identified by calbindin immunohistochemistry

Brain Res. 2003 Sep 5;983(1-2):230-2. doi: 10.1016/s0006-8993(03)03050-6.

Abstract

The dorsal cochlear nucleus (DCN) of Tree Shrews (Tupaia glis; n=2) was examined by calbindin (CB) immunohistochemistry for the presence of Purkinje-like cells (PLCs), detected previously in only four different mammals. We found up to eight CB-immunoreactive PLCs in the left and right DCN, and a few axons, likely of PLC origin, that appeared to leave the DCN. These findings suggest that PLCs may have a wider distribution through mammalian species, and may represent more than just misrouted cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Axons / physiology
  • Calbindins
  • Callithrix
  • Cochlear Nucleus / cytology
  • Cochlear Nucleus / physiology*
  • Functional Laterality / physiology
  • Guinea Pigs
  • Immunohistochemistry
  • Purkinje Cells / physiology*
  • Rats
  • S100 Calcium Binding Protein G / metabolism*
  • Tupaia / anatomy & histology*

Substances

  • Calbindins
  • S100 Calcium Binding Protein G