Synthesis of highly substituted 1,3-dienes and 1,3,5-trienes by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes

Xiaoxia Zhang; Richard C Larock

doi:10.1021/ol0348349

Synthesis of highly substituted 1,3-dienes and 1,3,5-trienes by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes

Org Lett. 2003 Aug 21;5(17):2993-6. doi: 10.1021/ol0348349.

Authors

Xiaoxia Zhang¹, Richard C Larock

Affiliation

¹ Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.

PMID: 12916964
DOI: 10.1021/ol0348349

Abstract

[reaction: see text] Highly substituted 1,3-dienes and trienes have been prepared in good to excellent yields by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes.