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. 2003 Jul;14(7):448-53.
doi: 10.1007/s00335-002-2261-9.

A Major Locus Conferring Susceptibility to Infection by Streptococcus Pneumoniae in Mice

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A Major Locus Conferring Susceptibility to Infection by Streptococcus Pneumoniae in Mice

Paul Denny et al. Mamm Genome. .

Abstract

We have studied the genetics of susceptibility to infection by Streptococcus pneumoniae in mice. Linkage analysis of the F(2) generation from a cross between resistant BALB/cO1aHsd and susceptible CBA/CaO1aHsd strains allowed us to map a major locus controlling the development of bacteremia and survival after intranasal infection.

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