The diagnosis of functional ovarian cysts using transvaginal ultrasound combined with clinical parameters, CA125 determinations, and color Doppler

Eur J Obstet Gynecol Reprod Biol. 2003 Sep 10;110(1):83-8. doi: 10.1016/s0301-2115(03)00209-4.

Abstract

Objectives: To investigate the role of transvaginal ultrasound combined with clinical parameters, CA125 determinations, and color Doppler in the differentiation between functional cysts and other adnexal masses.

Study design: Two hundred and eighty-seven consecutive persistent adnexal masses were submitted to B-mode transvaginal ultrasonography associated with color and power Doppler imaging. Plasma CA125 concentrations were measured before surgery.

Results: According to the obtained logistic regression equation, the presence of anechoic tumors without echogenic portions or septa and CA125 <25IU/ml was associated with a 75% probability of presence of follicular cysts. The visualization of fine trabecular jelly-like content or of a heterogeneous mass with hypoechoic content, absent or only peripheral arterial flow, and age <40 years was associated with a 56% probability of presence of luteal cysts.

Conclusions: Addition of findings to B-mode ultrasonography can help to differentiate functional cysts from other adnexal masses.

MeSH terms

  • Adolescent
  • Adult
  • CA-125 Antigen / blood*
  • Corpus Luteum
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Humans
  • Logistic Models
  • Middle Aged
  • Ovarian Cysts / diagnosis*
  • Ovarian Cysts / surgery
  • Ovarian Follicle
  • Sensitivity and Specificity
  • Ultrasonography / methods*
  • Ultrasonography, Doppler, Color*
  • Ultrasonography, Doppler, Pulsed
  • Vagina

Substances

  • CA-125 Antigen