[Antiarrhythmic active amidinohydrazones of substituted benzophenones. 3. The isomerization of (E)-2-amino-5-chlorobenzophenone amidinohydrazones]

P H Richter; A Besch; D Albrecht; K Kasbohm

[Antiarrhythmic active amidinohydrazones of substituted benzophenones. 3. The isomerization of (E)-2-amino-5-chlorobenzophenone amidinohydrazones]

Pharmazie. 1992 Dec;47(12):911-4.

[Article in German]

Authors

P H Richter¹, A Besch, D Albrecht, K Kasbohm

Affiliation

¹ Fachbereich Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.

PMID: 1293613

Abstract

The isomerization of the title compound in a preparative scale can be realized by acetylation/deacetylation or by influence of protons in dimethylformamide. The title compound is obtained als main product of the condensation of 2-amino-5-chlorbenzophenone and aminoguanidine if the reaction is carried out in the presence of formaldehyde.

Publication types

English Abstract

MeSH terms

Anti-Arrhythmia Agents / chemical synthesis*
Benzophenones / chemical synthesis*
Hydrazones / chemical synthesis*
Isomerism

Substances

Anti-Arrhythmia Agents
Benzophenones
Hydrazones