A convenient method for the preparation of inverted tert-alkyl carboxylates from chiral tert-alcohols by a new type of oxidation-reduction condensation using 2,6-dimethyl-1,4-benzoquinone

Teruaki Mukaiyama; Taichi Shintou; Kentaro Fukumoto

doi:10.1021/ja0303844

A convenient method for the preparation of inverted tert-alkyl carboxylates from chiral tert-alcohols by a new type of oxidation-reduction condensation using 2,6-dimethyl-1,4-benzoquinone

J Am Chem Soc. 2003 Sep 3;125(35):10538-9. doi: 10.1021/ja0303844.

Authors

Teruaki Mukaiyama¹, Taichi Shintou, Kentaro Fukumoto

Affiliation

¹ Center for Basic Research, The Kitasato Institute, 6-15-5 Toshima, Kita-ku, Tokyo 114-0003, Japan. Mukaiyam@abeam.ocn.ne.jp

PMID: 12940734
DOI: 10.1021/ja0303844

Abstract

Oxidation-reduction condensation using in situ-formed alkoxydiphenylphosphines, 2,6-dimethyl-1,4-benzoquinone, and carboxylic acids provided a new and efficient method for the preparation of inverted tert-alkyl carboxylates from various chiral tertiary alcohols.