Comment
doi: 10.1016/s0092-8674(03)00650-0.
Molecular recognition of cargo by the COPII complex: a most accommodating coat
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- PMID: 12941266
- DOI: 10.1016/s0092-8674(03)00650-0
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Molecular recognition of cargo by the COPII complex: a most accommodating coat
Cell.
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Abstract
The molecular mechanism by which diverse cargo proteins are recognized and exported from the ER has been unclear. Two papers in this issue of Cell add clarity by mapping multiple cargo recognition sites in the Sec24 subunit of the COPII coat complex and demonstrating roles for these sites in export of specific protein cargos from the ER.
Comment on
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SNARE selectivity of the COPII coat.Cell. 2003 Aug 22;114(4):483-95. doi: 10.1016/s0092-8674(03)00608-1. Cell. 2003. PMID: 12941276
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Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles.Cell. 2003 Aug 22;114(4):497-509. doi: 10.1016/s0092-8674(03)00609-3. Cell. 2003. PMID: 12941277
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