[The protective effect of Hippophae rhamnoides L. on hyperlipidemic serum cultured smooth muscle cells in vitro]

Zhongguo Zhong Yao Za Zhi. 1992 Oct;17(10):624-6, 601, inside back cover.
[Article in Chinese]


The effect of Hippophae rhamnoides on hyperlipidemic rabbit serum (HRS) cultured smooth muscle cells (SMC) was observed in comparison with vitamin E(VE). The results show that Hippophae rhamnoides, much like VE, is also a potent antioxidant. It strongly decreases the MDA content in HRS cultured SMC and protect the cells from the injury of lipid peroxidation, and thus keeps the SMC growing and proliferating health. The results implicate that Hippophae rhamnoides is an effective antioxidant, and one of the important mechanisms of Hippophae rhamnoides in anti-atherosclerosis reported recently may be closely related to the action of anti-lipid peroxidation.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Antioxidants / pharmacology*
  • Aorta
  • Cells, Cultured
  • Drugs, Chinese Herbal / pharmacology*
  • Embryo, Mammalian
  • Humans
  • Malondialdehyde / metabolism
  • Muscle, Smooth, Vascular / cytology
  • Muscle, Smooth, Vascular / drug effects
  • Muscle, Smooth, Vascular / metabolism*
  • Plant Oils / pharmacology
  • Superoxide Dismutase / metabolism


  • Antioxidants
  • Drugs, Chinese Herbal
  • Plant Oils
  • Malondialdehyde
  • Superoxide Dismutase