Small pulmonary nodules: volume measurement at chest CT--phantom study

Radiology. 2003 Sep;228(3):864-70. doi: 10.1148/radiol.2283020059.


Three-dimensional methods for quantifying pulmonary nodule volume at computed tomography (CT) and the effect of imaging variables were studied by using a realistic phantom. Two fixed-threshold methods, a partial-volume method (PVM) and a variable method, were used to calculate volumes of 40 plastic nodules (largest dimension, <5 mm: 20 nodules with solid attenuation and 20 with ground-glass attenuation) of known volume. Tube current times (20 and 120 mAs), reconstruction algorithms (high and low frequency), and nodule characteristics were studied. Higher precision was associated with use of a PVM with predetermined pure nodule attenuation, high-frequency algorithm, and diagnostic CT technique (120 mAs). A PVM is promising for volume quantification and follow-up of nodules.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Lung Diseases / diagnostic imaging*
  • Phantoms, Imaging*
  • Tomography, X-Ray Computed / methods*