Outbreak of serogroup C meningococcal disease caused by a variant of Neisseria meningitidis serotype 2a ET-15 in a community of men who have sex with men

Raymond S W Tsang; Lori Kiefer; Dennis K S Law; Jan Stoltz; Rita Shahin; Shirley Brown; Frances Jamieson

doi:10.1128/JCM.41.9.4411-4414.2003

Outbreak of serogroup C meningococcal disease caused by a variant of Neisseria meningitidis serotype 2a ET-15 in a community of men who have sex with men

J Clin Microbiol. 2003 Sep;41(9):4411-4. doi: 10.1128/JCM.41.9.4411-4414.2003.

Authors

Raymond S W Tsang¹, Lori Kiefer, Dennis K S Law, Jan Stoltz, Rita Shahin, Shirley Brown, Frances Jamieson

Affiliation

¹ National Microbiology Laboratory, Population and Public Health Branch, Health Canada Winnipeg, Manitoba, Canada. rtsang@hc-sc.gc.ca

Abstract

We describe an outbreak, in a community of men who have sex with men, of serogroup C meningococcal disease caused by a genetic variant of the serotype 2a ET-15 Neisseria meningitidis characterized by a point mutation in the gene coding for the serotype 2a antigen. A microbiological characterization of the outbreak strain is presented in this report.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
DNA, Bacterial / analysis
Disease Outbreaks*
Electrophoresis, Gel, Pulsed-Field
Homosexuality, Male*
Humans
Male
Meningococcal Infections / epidemiology*
Meningococcal Infections / etiology
Molecular Sequence Data
Neisseria meningitidis / classification*
Neisseria meningitidis / genetics
Polymerase Chain Reaction
Serotyping

Substances

DNA, Bacterial

Associated data

GENBANK/AY234206
GENBANK/AY234207
GENBANK/AY234208
GENBANK/AY234209
GENBANK/AY234210
GENBANK/AY234211