Hepatic failure with flutamide

Indian J Gastroenterol. 2003 Jul-Aug;22(4):149-50.

Abstract

A 41-year-old woman, who was on flutamide for hair loss for 3 months, presented with deep jaundice. She developed hepatic encephalopathy but gradually recovered after discontinuing flutamide. Flutamide can cause fatal toxic liver injury and hence should be used with close monitoring of liver profile.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Androgen Antagonists / adverse effects*
  • Androgen Antagonists / toxicity*
  • Female
  • Flutamide / adverse effects*
  • Flutamide / toxicity*
  • Hair Diseases / complications
  • Hair Diseases / drug therapy
  • Humans
  • Jaundice / chemically induced
  • Liver Failure / chemically induced*

Substances

  • Androgen Antagonists
  • Flutamide