Malignant acanthosis nigricans and endometrioid adenocarcinoma of the parametrium: the search for malignancy

J Am Acad Dermatol. 2003 Sep;49(3):541-3. doi: 10.1067/s0190-9622(03)00913-7.

Abstract

Malignant acanthosis nigricans is recognized as a cutaneous sign of internal malignancy, usually an adenocarcinoma. Although cases of malignant acanthosis nigricans have been associated with cervical, ovarian, and endometrial neoplasms, we describe a case with a rarely if ever reported association, endometrioid adenocarcinoma of the parametrium.

Publication types

  • Case Reports

MeSH terms

  • Acanthosis Nigricans / complications*
  • Acanthosis Nigricans / pathology
  • Adenocarcinoma / etiology*
  • Adenocarcinoma / pathology
  • Adenocarcinoma / therapy
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy, Needle
  • Carboplatin / administration & dosage
  • Chemotherapy, Adjuvant
  • Endometrial Neoplasms / etiology*
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Hysterectomy / methods
  • Immunohistochemistry
  • Paclitaxel / administration & dosage
  • Risk Assessment
  • Treatment Outcome

Substances

  • Carboplatin
  • Paclitaxel