[The influence of anxiety, depression and post traumatic stress disorder on quality of life after thoracic organ transplantation]

Z Psychosom Med Psychother. 2003;49(3):262-74. doi: 10.13109/zptm.2003.49.3.262.
[Article in German]


Objectives: This study examines stress factors, resources of coping, psychopathological symptoms and their influence on health-related quality of life (QoL) in patients after heart or lung transplantation.

Methods: 82 Patients were examined with the questionnaires SF-36 (QoL), HADS-D (anxiety and depression), IES-R and PTSS-10 (post traumatic stress disorder, PTSD) 32.3 (4-86) months after transplantation. Stress factors, resources and diagnostic criteria for PTSD were investigated by structured interview.

Results: In the entire sample, anxiety, depression and QoL were in the range of normal population. A subgroup of 13 patients with a PTSD diagnose had significantly reduced QoL. Anxiety and intrusion explained the 42 % variance of psychosocial score of QOL.

Conclusions: There was a lower influence of depression on the medical score of QoL. Psychological symptoms such as anxiety, depression and PTSD significantly influence QoL after heart or lung transplantation. Patients with a PTSD diagnose had poor QoL. Screening for PTSD should be part of routine evaluation after organ transplantation.

Publication types

  • English Abstract

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Aged
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / psychology*
  • Cost of Illness
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology*
  • Female
  • Follow-Up Studies
  • Heart Transplantation / psychology*
  • Heart-Lung Transplantation / psychology*
  • Humans
  • Lung Transplantation / psychology*
  • Male
  • Middle Aged
  • Personality Inventory
  • Postoperative Complications / psychology*
  • Quality of Life / psychology*
  • Sick Role*
  • Social Support
  • Stress Disorders, Post-Traumatic / diagnosis
  • Stress Disorders, Post-Traumatic / psychology*