Shaping and stretching life by autophagy

Dev Cell. 2003 Sep;5(3):364-5. doi: 10.1016/s1534-5807(03)00269-7.

Abstract

In a recent study published in Science, demonstrate that genes required for autophagy act downstream of insulin-like signaling, and are involved in the expression of major life history traits, including dauer larva development and adult life span.

MeSH terms

  • Animals
  • Autophagy / physiology*
  • Caenorhabditis elegans
  • Caenorhabditis elegans Proteins / physiology
  • Insulin / physiology*
  • Larva
  • RNA, Small Interfering / metabolism
  • Signal Transduction / physiology*
  • Vesicular Transport Proteins
  • Yeasts

Substances

  • Caenorhabditis elegans Proteins
  • Insulin
  • RNA, Small Interfering
  • Vesicular Transport Proteins
  • bec-1 protein, C elegans