Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil

Res Virol. Nov-Dec 1992;143(6):423-7. doi: 10.1016/s0923-2516(06)80136-6.


The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months after onset. MAC-ELISA proved to be a valuable early diagnosis test when compared with haemagglutination inhibition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / blood*
  • Brazil / epidemiology
  • Dengue / epidemiology*
  • Dengue / immunology
  • Dengue Virus / immunology*
  • Disease Outbreaks*
  • Enzyme-Linked Immunosorbent Assay
  • Hemagglutination Inhibition Tests
  • Humans
  • Immunoglobulin M / blood*
  • Immunoglobulin M / immunology


  • Antibodies, Viral
  • Immunoglobulin M