Imiquimod 5% cream for keloid management

Dermatol Surg. 2003 Oct;29(10):1050-1. doi: 10.1046/j.1524-4725.2003.29300.x.

Abstract

Background: Keloid treatment represents a therapeutic challenge. New adjuvant therapy is needed to reduce the high recurrence rate (50%) of excised keloids.

Objective: To describe the method for using imiquimod 5% cream in the prevention of keloid recurrence after surgery.

Methods: This is a review of the scientific rationale and clinical experience of using imiquimod 5% cream for keloid management.

Conclusion: Topical application of imiquimod 5% cream after surgery reduces keloid recurrences.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adjuvants, Immunologic / administration & dosage*
  • Administration, Topical
  • Aminoquinolines / administration & dosage*
  • Chemotherapy, Adjuvant / methods
  • Humans
  • Imiquimod
  • Keloid / drug therapy*
  • Keloid / prevention & control*
  • Keloid / surgery
  • Secondary Prevention
  • Surgical Procedures, Operative

Substances

  • Adjuvants, Immunologic
  • Aminoquinolines
  • Imiquimod