Retinal detachment is an eye with a keratoprosthesis usually has an extreme poor prognosis. We describe the successful repair of a total retinal detachment following implantation of a new type Worst-keratoprosthesis in the only eye of a 70-year-old patient. A vitrectomy, epiretinal peeling, 180 degrees superior retinotomy, subretinal membrane peeling and an injection of perfluorooctane were performed to flatten the retina. After the endophotocoagulation a perfluorooctane-silicone oil exchange was performed. An additional intervention was necessary to treat a redetachment. After 3 months follow-up the retina has remained attached and the patient regained ambulatory vision.