Human papillomavirus type 42: new sequences, conserved genome organization

Virology. 1992 Jan;186(1):331-4. doi: 10.1016/0042-6822(92)90091-3.


We report the nucleotide sequence and genome organization of the human papillomavirus type 42. HPV42 DNA was isolated from vulvar papillomas. It has been detected in benign forms of proliferative lesions only. The genome of HPV42 is 7917 bp long and shows the open reading frame pattern conserved in all HPVs sequenced so far. HPV42 has no high degree of sequence homology to any of the known HPVs. It shows characteristics previously found either exclusively in HPVs associated with invasive carcinomas or exclusively in nongenital HPVs. Therefore it cannot be readily ascribed to any of the established subgroups of human papillomaviruses.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA, Viral / genetics
  • Enhancer Elements, Genetic
  • Genes, Viral
  • Molecular Sequence Data
  • Papillomaviridae / genetics*
  • Promoter Regions, Genetic
  • Regulatory Sequences, Nucleic Acid
  • Viral Structural Proteins / genetics


  • DNA, Viral
  • Viral Structural Proteins