A comparison of risk factors in juvenile-onset and adult-onset recurrent respiratory papillomatosis

Laryngoscope. 1992 Jan;102(1):9-13. doi: 10.1288/00005537-199201000-00002.

Abstract

The clinical triad of a firstborn delivered vaginally to a young (teenage) mother has been previously noted among juvenile onset recurrent respiratory papillomatosis (JO-RRP) patients. This study was based on a questionnaire survey of JO-RRP patients, adult onset recurrent respiratory papillomatosis (AO-RRP) patients, and juvenile and adult controls. The survey results revealed that the complete or partial triad was observed in 72% of JO-RRP patients, 36% of AO-RRP patients, 29% of juvenile controls, and 38% of adult controls. As compared with juvenile controls, JO-RRP patients were more often firstborn (P less than .05), delivered vaginally (P less than .05), and born to a teenage mother (P less than .01). Among adult participants, AO-RRP patients reported more lifetime sex partners (P less than .01) and a higher frequency of oral sex (P less than .05) than reported by adult controls. AO-RRP and JO-RRP appear to have distinguishable epidemiologic features indicating that the mode of human papillomavirus (HPV) transmission is different in these two disorders.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Birth Order
  • Child
  • Child, Preschool
  • Cocarcinogenesis
  • Delivery, Obstetric
  • Female
  • Humans
  • Male
  • Maternal Age
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Papilloma / epidemiology*
  • Papillomaviridae*
  • Respiratory Tract Neoplasms / epidemiology*
  • Risk Factors
  • Sexual Behavior
  • Sexual Partners
  • Tumor Virus Infections / epidemiology*
  • Tumor Virus Infections / transmission