Surgical repair of rhegmatogenous retinal detachment in immunosuppressed patients with cytomegalovirus retinitis

Ophthalmology. 1992 Mar;99(3):466-74. doi: 10.1016/s0161-6420(92)31976-1.


The authors performed retinal reattachment surgery in 29 eyes of 24 patients with acquired immune deficiency syndrome virus with retinal detachment associated with cytomegalovirus (CMV) retinitis and documented the course of eight additional untreated eyes. Retinal detachment repair using vitrectomy, posterior hyaloid removal, and intraocular tamponade with silicone oil or SF-6 gas resulted in a total retinal reattachment rate of 76% and a macular attachment rate of 90% in one operation. The mean postoperative visual acuity (best corrected) was 20/60, but, in some patients, the visual acuity decreased because of progressive retinitis. Prophylactic laser photocoagulation of fellow eyes to surround CMV lesions did not appear to prevent retinal detachment. The mean postoperative survival was 37 weeks (range, 8 to 127 weeks). The surgical techniques used and pathophysiology of these retinal detachments are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Cytomegalovirus Infections / complications*
  • Eye Infections, Viral / complications*
  • Fundus Oculi
  • Humans
  • Immunocompromised Host*
  • Male
  • Middle Aged
  • Postoperative Complications
  • Retinal Detachment / complications
  • Retinal Detachment / surgery*
  • Retinitis / complications*
  • Retinitis / microbiology
  • Treatment Outcome
  • Visual Acuity
  • Vitrectomy