Fatal disseminated infection with human herpesvirus-6

J Pediatr. 1992 Jun;120(6):921-3. doi: 10.1016/s0022-3476(05)81962-6.


A 13-month-old immunocompetent girl had fever, rash, and multisystem disease, and she eventually died of cardiac failure. Autopsy revealed intracellular viral inclusions of the herpesvirus group, with results of in situ hybridization positive for human herpesvirus-6. This is apparently the first case of fatal disseminated herpesvirus-6 infection.

Publication types

  • Case Reports

MeSH terms

  • Exanthema Subitum / microbiology*
  • Female
  • Herpesviridae Infections / epidemiology*
  • Herpesviridae Infections / microbiology
  • Herpesvirus 6, Human / isolation & purification*
  • Humans
  • Inclusion Bodies, Viral / microbiology
  • Infant
  • Lymphocytes / microbiology
  • Microscopy, Electron
  • Nucleic Acid Hybridization
  • Spleen / microbiology