Proofreading, NTPases and translation: successful increase in specificity

M Yarus

doi:10.1016/0968-0004(92)90257-a

Proofreading, NTPases and translation: successful increase in specificity

Trends Biochem Sci. 1992 May;17(5):171-4. doi: 10.1016/0968-0004(92)90257-a.

Author

M Yarus¹

Affiliation

¹ Department of MCD Biology, University of Colorado, Boulder 80309-0347.

PMID: 1317614
DOI: 10.1016/0968-0004(92)90257-a

Abstract

The discussion of proofreading started in the April issue of TIBS is completed by treating the two branched Michaelis-Menten enzymes that can proofread. The conditions required for proofreading can be seen to determine the expression of proofreading in its biological settings. There are surely instances of proofreading as yet unrecognized.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Kinetics
Nucleoside-Triphosphatase
Phosphoric Monoester Hydrolases / physiology*
Protein Biosynthesis / physiology*
Substrate Specificity

Substances

Phosphoric Monoester Hydrolases
Nucleoside-Triphosphatase

Grants and funding

GM30881/GM/NIGMS NIH HHS/United States