Cardiac output response to altered acid-base status during diethyl ether anaesthesia

Can Anaesth Soc J. 1975 Nov;22(6):673-9. doi: 10.1007/BF03013315.

Abstract

The effects of acid-base changes on cardiac output during diethyl ether anaesthesia were studied in 25 mongrel dogs prepared by surgically implanting a plastic encased non-ferrous core electromagnetic probe on the ascending aorta. The findings are: (1) Metabolic acidaemia produced only slight decrease in cardiac output but a more marked fall became evident with decreasing pH(2) Respiratory acidaemia led to a slight rise in cardiac output. (3) Respiratory alkalaemia decreased cardiac output. (4) Metabolic alkalaemia also produced a decline in cardiac output.

MeSH terms

  • Acid-Base Equilibrium*
  • Acidosis / blood
  • Acidosis / chemically induced
  • Acidosis, Respiratory / blood
  • Acidosis, Respiratory / chemically induced
  • Alkalosis / blood
  • Alkalosis / chemically induced
  • Alkalosis, Respiratory / blood
  • Anesthesia, Inhalation*
  • Animals
  • Bicarbonates
  • Blood
  • Carbon Dioxide / blood
  • Cardiac Output*
  • Dogs
  • Ether*
  • Ethyl Ethers*
  • Hydrochloric Acid
  • Hydrogen-Ion Concentration
  • Hypoxia / blood
  • Male
  • Oxygen / blood

Substances

  • Bicarbonates
  • Ethyl Ethers
  • Ether
  • Carbon Dioxide
  • Hydrochloric Acid
  • Oxygen