Pain-related somatosensory evoked potentials following CO2 laser stimulation in peripheral neuropathies

Acta Neurol Scand. 1992 May;85(5):347-52. doi: 10.1111/j.1600-0404.1992.tb04058.x.


Pain-related somatosensory evoked potentials (pain SEPs) following CO2 laser stimulation were examined in 30 patients with peripheral neuropathies, and the results were compared with clinical sensory findings. Pain SEP findings showed a significant correlation with the clinical impairment of pain sensation, but not with the impairment of deep sensations. In contrast, conventional electrically-stimulated SEPs (electric SEPs) showed a significant correlation with deep sensations, but not with the impairment of pain sensation. Examinations of both pain SEPs and electric SEPs, therefore, are considered to be very useful to evaluate physiological functions of sensory nerves in patients with peripheral neuropathies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Carbon Dioxide
  • Electric Stimulation
  • Evoked Potentials, Somatosensory / physiology*
  • Female
  • Humans
  • Lasers*
  • Male
  • Neural Conduction
  • Pain / physiopathology
  • Pain Management*
  • Peripheral Nervous System Diseases / physiopathology
  • Peripheral Nervous System Diseases / therapy*


  • Carbon Dioxide