High-affinity kainate and domoate receptors in rat brain

FEBS Lett. 1992 Jul 28;307(2):139-43. doi: 10.1016/0014-5793(92)80753-4.

Abstract

Mammalian brain expresses receptors which bind the potent neurotoxins, kainate and domoate, with high affinity, and which form a subclass of ionotropic glutamate receptors. A new member of these receptors, expressed in both adult and embryonic CNS is compared in its ligand binding properties to its closely sequence-related homologs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Brain / metabolism*
  • DNA
  • Glutamates / metabolism
  • Kainic Acid / analogs & derivatives*
  • Kainic Acid / metabolism*
  • Molecular Sequence Data
  • Rats
  • Receptors, Glutamate
  • Receptors, Kainic Acid
  • Receptors, Neurotransmitter / chemistry
  • Receptors, Neurotransmitter / metabolism*
  • Sequence Alignment

Substances

  • Glutamates
  • Receptors, Glutamate
  • Receptors, Kainic Acid
  • Receptors, Neurotransmitter
  • DNA
  • domoic acid
  • Kainic Acid

Associated data

  • GENBANK/Z11712
  • GENBANK/Z11713
  • GENBANK/Z11714
  • GENBANK/Z11715
  • GENBANK/Z11716