The DNA polymerase-encoding gene of Bacillus subtilis bacteriophage SPO1

Gene. 1992 Sep 1;118(1):109-13. doi: 10.1016/0378-1119(92)90256-o.


The bacteriophage SPO1 DNA polymerase-encoding gene, which contains a self-splicing intron, has been sequenced and its amino acid (aa) sequence has been deduced. The aa sequence of SPO1 DNA polymerase shows a high degree of similarity with that of DNA polymerase I from Escherichia coli (Po1I). Alignment with the sequences of Po1I, and the phi 29 and SPO1 DNA polymerases indicate that the aa residues that have been implicated in 3'----5' exonuclease activities are conserved.

Publication types

  • Comparative Study

MeSH terms

  • Amino Acid Sequence
  • Bacillus subtilis*
  • Bacteriophages / enzymology*
  • Bacteriophages / genetics
  • Base Sequence
  • DNA Polymerase I / genetics*
  • Escherichia coli / genetics
  • Exonucleases / metabolism
  • Introns / genetics
  • Molecular Sequence Data
  • Restriction Mapping
  • Sequence Homology, Nucleic Acid


  • DNA Polymerase I
  • Exonucleases

Associated data

  • GENBANK/M74891
  • GENBANK/M74892
  • GENBANK/M79309
  • GENBANK/M79310
  • GENBANK/M84415
  • GENBANK/M88536
  • GENBANK/M88537
  • GENBANK/M88538
  • GENBANK/M88539
  • GENBANK/M90357