Metastatic choriocarcinoma with coexistent term pregnancy following four recurrent consecutive moles

Acta Obstet Gynecol Scand. 1992 Jul;71(5):401-3. doi: 10.3109/00016349209021083.

Abstract

A case is reported of a 38-year-old woman with metastatic choriocarcinoma which followed four recurrent consecutive hydatidiform moles occurring within the preceding 5-year period. She conceived while having pulmonary metastasis, had a coexistent normal pregnancy and delivered a normal infant at term. Surgical resection of the lung lesion together with chemotherapy accomplished a sustained remission, with no evidence of disease after 20 months' follow-up.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Choriocarcinoma / diagnosis*
  • Choriocarcinoma / drug therapy
  • Cyclophosphamide / administration & dosage
  • Dactinomycin / administration & dosage
  • Etoposide / therapeutic use
  • Female
  • Humans
  • Hydatidiform Mole / complications*
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery
  • Methotrexate / administration & dosage
  • Platinum / therapeutic use
  • Pregnancy
  • Pregnancy Complications, Neoplastic*
  • Uterine Neoplasms*

Substances

  • Dactinomycin
  • Platinum
  • Etoposide
  • Cyclophosphamide
  • Methotrexate