Delayed c-fos expression in sensory cortex following sexual learning in male rats

Brain Res Mol Brain Res. 1992 Aug;14(4):352-6. doi: 10.1016/0169-328x(92)90103-i.


An elevated expression of c-fos protooncogene, encoding transcription factor Fos, is known to serve as a useful marker of neuronal activation. In the studies reported in this communication we have used Northern and dot blot techniques to analyze c-fos mRNA levels in male rat brain during the learning of the copulatory behavior. The animals were trained (single ejaculation in a training/testing session) for up to 7 sessions. C-fos mRNA levels have been found to increase in the sensory cortex area following the third and fifth session but not after the first and the last one.

MeSH terms

  • Animals
  • Ejaculation / physiology
  • Gene Expression Regulation / physiology*
  • Genes, fos / genetics*
  • Learning / physiology*
  • Male
  • Rats
  • Rats, Inbred Strains
  • Reaction Time / physiology
  • Sexual Behavior, Animal / physiology*
  • Somatosensory Cortex / physiology*