Relapsing acute disseminated encephalomyelitis associated with chronic Epstein-Barr virus infection: MRI findings

Neuroradiology. 1992;34(4):340-2. doi: 10.1007/BF00588198.


A 25-year-old women had a fever, left cervical lymphadenopathy, neurological symptoms and signs, CSF pleocytosis and persistent high serum antibodies to the Epstein-Barr virus (EBV); she had a recurrence 1 year later. She was thought to have relapsing acute disseminated encephalomyelitis associated with chronic EBV infection. MRI revealed abnormalities, mainly in the right basal ganglia and left midbrain. At the time of the recurrence, further abnormalities appeared in the opposite basal ganglia and right cerebral white matter.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Viral / analysis
  • Antigens, Viral / immunology
  • Brain / pathology
  • Capsid Proteins*
  • Chronic Disease
  • DNA-Binding Proteins / immunology
  • Encephalomyelitis / diagnosis*
  • Epstein-Barr Virus Nuclear Antigens
  • Female
  • Herpesvirus 4, Human* / immunology
  • Humans
  • Infectious Mononucleosis / diagnosis*
  • Magnetic Resonance Imaging*
  • Recurrence


  • Antibodies, Viral
  • Antigens, Viral
  • Capsid Proteins
  • DNA-Binding Proteins
  • Epstein-Barr Virus Nuclear Antigens
  • Epstein-Barr viral capsid antigen