The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake

Diabetes Metab Rev. 1992 Oct;8(3):259-85. doi: 10.1002/dmr.5610080305.
No abstract available

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Blood Glucose / metabolism
  • Cell Division / drug effects
  • Growth Substances / pharmacology
  • Humans
  • Insulin / analogs & derivatives*
  • Insulin / chemistry
  • Insulin / metabolism*
  • Insulin / pharmacology
  • Kinetics
  • Models, Molecular
  • Protein-Tyrosine Kinases / metabolism
  • Receptor, IGF Type 1 / metabolism
  • Receptor, Insulin / metabolism*
  • Recombinant Proteins / metabolism
  • Recombinant Proteins / pharmacology

Substances

  • Blood Glucose
  • Growth Substances
  • Insulin
  • Recombinant Proteins
  • Protein-Tyrosine Kinases
  • Receptor, IGF Type 1
  • Receptor, Insulin